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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abc65175b3d6108120e33579b4f5d94229c4fd7b37d093482cb23cc3370a2518' 
  AND token = '2y5Y8sVOAj//AOtimGP/Oy/0/kYURZafEdROwzjc5rg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}