SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e547bf3937c9f380749f671ba1326e771b0d2ed71ef0e57193393056b9a4624d' 
  AND token = 'PM/km7aMcsy47xyZlXogTiUZ/6jvk+5Z1giDY5opZTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}