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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41355c4eec00c6e87f31d1f6bfe49b75f6b9c5280cba80c5736133ed43593743' 
  AND token = 'cClE7mLzJ+U1zKvcyjM3Z+8WyZ4ZMLFWH2mOZmCy/oY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}