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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e27e276f0d643332d73133aaee172071aa70a78dd45b9cae52863ec5b72ee85' 
  AND token = 'XznuMoPSh9Xja1Uk5anBFykZRW4oPYVzEqgXA+cnZ7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}