SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24bc33985e421049510cc0fc2fa4ed15bef440c52c34dc4bc8d8e9b3e5279fb3' 
  AND token = 'hTVSyP3hPHrVkxEbX7CQzaxojj9FkQ87q5oxAeWlNcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}