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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0949751757d9e78ab36154d042a38260ca101c1db6e4516f5ec06601c97644a2' 
  AND token = 'HdqtHAGkLsuG6Cw3DOyH84qsdDk+4wku5oP+B/q3TGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}