SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '108b4434850bc769f0d606031fea645fa46ea1fcc9d943bb297a4b48099eb88f' 
  AND token = 'E+7JkXCO1h2QWmWoDS5U9gJXqMSNPvRJAHAyi5OPKEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}