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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3dbe854bf3285cfad9b71d49e066a898d4997b1f6b814e52eeb7ddee6ae7160' 
  AND token = '4zVnKl+JGOfN4dQZD9I3GCr5VupBu6p4QAiWl6FT3Y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}