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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25793181b138cb608dee9dfdbd00f7fe7cbc063c6a65fbd23f0cecc4efe75148' 
  AND token = 'd77tNlP27kxk1K6SNumCn+4MoO90PaxBDj3DYuNGVmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}