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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae3bf504e4e108b20be35aa34e925fe5f42531384025de6fedae9648fbb88104' 
  AND token = 'h48M/qTeubgGS5x2heQbNVUQjTuSjrVIbSpBztDM180=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}