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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b3857544e2f522a123e4f1997a78bc72847d8ff4a293ec4063dcb4feb4ad20f' 
  AND token = 'a1Bh9MDv9tZFH0tmSCiDyUI/v2vHan9FP078NmBSLAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}