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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb7b018e0d603b7760d994c15e06755d5df5f67521a9d6c1e0513dd3dab3fa56' 
  AND token = 'T3zB8mOx75HzwkuPGuWv5T1d0nNlyy9VX5z9acQ6Yrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}