SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd4cabe7af9a96610c7fb57c9018832e612a8b9e8a17e100f5d298656f08c849' 
  AND token = 'j4nllZ9YFktgArqDG02R4jaFQOgxZ5NhnWFvuozDtyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}