SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf6fccc2e07eab750db3e1836de6824d7325bfadcf973ba63dbd41f31801b63a' 
  AND token = 'HVi9H1Udy0Mcbjb5BvNUkMSRF4JfEUIis6mIdBbOiXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}