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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df1532261e31d39dfef1ac6fcf9c6afdba0199d2afd9ff0da30812b03b16bfc4' 
  AND token = '/kOyM4NDXxDy8KSB2FUxpLHcg7uJEZ8i1cu0dMrN1g4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}