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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0074939d46f4bcc07558170d4709b9a359216c340937f732cb4f39fbaf94980' 
  AND token = 'rSjapEgC+zFfiEVEygbJppAwdPO5SxQsYbewCZhCxfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}