SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0673815998cf9f1a71a0d4078037fba862cbb35a9ded7e2ecdc4f1ea45156ff5' 
  AND token = '0tYYoifV4FFr+YGN5+xQVL2Y7r91qaJJA5LPPcVpeZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}