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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3c917b8367534dc4cbe4e06de3e3f1ba467f01f76561c215948c753bb6b9d0e' 
  AND token = 'ptfQiq/sVxdf1h18Fr/e9w6uukQXYeHfX82mWrPdLGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}