SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad964a898a4b784d963d10e0ba5a35cd77c13beebffb2c4f65e4f9ee498c2326' 
  AND token = 'QNRWheksqA0j7pOP7auss8Xfa3KmB0vv1QaN+NyfSp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}