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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '362af74c44ae114814bfe43f35f857a8db14e6974172ae8d297eec840d49af26' 
  AND token = 'PoU+RLTCjAUDlWzExmghBZgT2T49yAfEi5oLjUpfGxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}