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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0564473bc442254198aaf9d55eadbd68f74442d36f99d95a772bfa665e6c22b1' 
  AND token = 'SDXqTxbyMVfy1gsdRwNh292VFpfwVG2dIn5YLXmXWC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}