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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8867e7a30b03301855ef7a63fd7e4387fc8107bd0ab299a9b5d88813673c7d48' 
  AND token = 'S99DgeV0xb+Ce1bmZy6vkBCgUkQdxL3/NXIc3kZPfE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}