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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0de01dbfc6475eb922f84438a42466d563f1a707edeb1b731a205bf15a3962a0' 
  AND token = 'sRPrl2UlMkhAhiJL8XpokAa7GXO3uaIsgNmv1IJhuCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}