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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '248853be1965fb5cf8c8781c493331b267dd2d942768228ca21cb50032e7c26b' 
  AND token = '/7XwgOu3d80BOPrtY3WzaeO4OJFIO2/XsLTcMzNUgUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}