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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef95f494a2cef0acda6eb722cc0f1f25a0bde06621555d0244e15d1ad981f59b' 
  AND token = 'trcSGLBW0M42yyMvmp7cxHMH+ocgynyLM/FlOle+GPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}