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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae3756bb50e8cfa38fd527a52c87e497e6db1b03adebfb5d4470def8738c653e' 
  AND token = 'DW4HfnDgIr0+JUYrDbz2VlXvE3cnj8NSubOjk4F15eU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}