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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16616fc5f1ba8f5a65255da861fd0d4a559eb945a321a78c42d5e782c5c3c425' 
  AND token = 'ZOQBwGT6md1V0gmfZNC+0X33Ce36AsA257tx5i0uODQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}