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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57c9ae780ed2ddd317d78be611b9b013f43bc6ad3eb50bf735eecfd00c44ede6' 
  AND token = 'Fx4F03YPsh9oENJbVR3JVoQFyGKn+Q80KjgIsrC8WNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00076

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}