SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '425436abcb270d7fcaad65322645731c6a79bb3909ffa771a4cb857a9e31e40f' 
  AND token = 'vALrunKac96WckzQASUWYwxyQZWAUzTeTM8YJrs6iF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}