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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b9b351ee5da15eda03c1d53d0b5fb3e7dd966d405137cdf7339674bd456bc67' 
  AND token = 'V3xib/uCpjs3Wh8wqV5sUNzKVSMO7wDOW3mZ6VSDnyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}