SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cfa45e4eac46c02f52383f83eb6dfb9999594b6a94f7d06a53d29638f5e8506' 
  AND token = 'CHlqqFZPJb1kNb1votbxxFpm6oGG/rTKloiQR1gHHCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}