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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a0d5b60bd36a5f501e0275aa217ce097c0d45cc323c9168f6703600a3e5461a' 
  AND token = 'F1YuFlqfFfqn4PfmkUmh/SaScgaA2i/XSKaJVMjWvsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}