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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a665b732adc08123a62372f1f3e026a872ac98d86c57b7d8fabbf8a90b5930b2' 
  AND token = 'puuoQsyyFR+ZhxFCjpAngdSsUCmgnLpU3lxXsQdr7wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}