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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9572ee66e38e107bd85508381134754bbde84f8dc75f3eb9e009cf8775fd7b1' 
  AND token = 'W3b6nW69pOOvND95NoiOyUyOQZgQxtHGxumjvc0Trgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}