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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef376fd5ffe4c274c0e3d111d5dcc48b28d34f2b574f480fa5a4b2a0cf220714' 
  AND token = 'NRscN5+DTzOlztEeF76sVadolJ3m5U5tVNtwD30ibsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}