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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46519a1d97e7ae805c0274779bd43916b21f7bb0c20f0cd1b26330ba8f1d3723' 
  AND token = 'ROgtuH6pvTaoE5DVBcOo4k5jrA2JiKqW6poLxK8ZWSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}