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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b3bd7b9a91600817ceb4bb4980b9df20847fe2ac207e67e9cd3c952f957ce59' 
  AND token = 'nKRLrNh6WDS0nbJ0WfCKPTtM8StBiHdlOBrCEwnmTGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}