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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '240ad4a245c985294519a94585ccdf8ee1f0b2da7ae9c0d7492c4be3de646275' 
  AND token = 'HXHcXM8h+oN1TSxMDPonRWmI8AnSsovvIv+bns/06nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}