SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '846ecaa456c7fd9977a08a14f0fa85d819f14b2a2aaf6440c62efef29b972e1b' 
  AND token = 'VGVB3jQPHsBmPARIlIIjU+cdxaORz1YQ82c2WILSCzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}