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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8961e749b4b70b32114dd4fd6c9f3f23003e6926f485a0be59618716fcf01779' 
  AND token = 'HQg4JoyOcHoaPevc9yVGZxpqruuUoS0E/eMJmjHBo3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}