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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46b33598b63223f84b4318e90cf2b2b62771188245b04ef66fa690b416574bcc' 
  AND token = 'xjt2Y+TSdZzjcd6eCnB6gajbPasweoEbq6veifRFKAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}