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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e5bd8b0d658eee74fee7a64a3634aa256b56f72b4830e5d2cb9fb9d5d04c481' 
  AND token = '5CRwhpjeAG0h4Uyp4UCp2B90zH5Y+mOSge/VkrekeBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}