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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fb7c6eae99d067022da3e8f38defd1f5b6dce9b6ef1766607b5e99ef05faf43' 
  AND token = 'sCfp6/ZbViFl0N7DvWrlbFgWxYS1xzrRwYB5a6A1B8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}