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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04b6d1ba011abb01993dc97183b60ad7bfe3558b53a379abaa45c65d1e53fdd4' 
  AND token = 'kmvVkA0q09YlzcH/FFPUQNqcjbcqTJs6FOfLdArfE8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}