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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27f53cde284a75e4cceb971bd8db70e6755b03f8d617545cdc4a874336742278' 
  AND token = 'YIMz2V+cNUP8mwyrLDWACKusMyO33L1Ljk2yzoK78Sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}