SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bd178675cb56ccd66f575bc2a46903119b785e0f92d0c40d71cd2abae5d2775' 
  AND token = 'W8exkiw2KkKVwAJkF2s5CjkSktCiOc5DMXxVNxFaZgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}