SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f719b68ad3e8bb261f0b016ae6921f08f32a404b77b78535f1e9e8c5052ca43e' 
  AND token = '+eOe5r/Zg+RPOyr6P0o0N2IqVzUwoSJem6GfiYjS4Lo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}