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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecde24a87285911cec6bbda964ad96453f146ca08009717c7bf2334459cd32ad' 
  AND token = '+4sjUoQiaCLe4wSxm3zgsrJe/dJ4Wx4tDpTr77yYK/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}