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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '782615714cd663be593d5a06583574d1639dbb715f05cfc0bdf8c06006abad45' 
  AND token = 'Jz4QkTZfNcRaPN/PLrP+Jejz2TpfAC5o1mUp9m2+MDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}