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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54199eaefcd5dc990a32e52e944f8c4cb3c4e32d2bb056057bab9b6f29b77409' 
  AND token = '4aIBouzeHV39wNphMZeUlCtadsn62En/6ZiyZSrt7a8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}